How it's made

We start with the cells that renew the lining of the uterus every cycle.

The endometrium, the lining of the uterus, is the only adult human tissue that renews itself every cycle. The cells shed in menstrual blood have just taken part in that process. That is why we collect it, and why the stem cells it contains are the starting point for everything we make.

From a donor's sign-up to the finished ingredient. Schematic, not to scale. Click to pause.

The process

From a donor's kit to the ingredient.

  1. Donor

    A donor signs up, answers the eligibility questions and signs a consent form in the donor portal.

  2. Kit

    A collection kit arrives at home. The donor collects with a menstrual cup and sends the sample back the same day with the prepaid label.

  3. Lab

    The sample reaches our laboratory chilled and coded, and is checked on arrival. The donor's name never travels with it.

  4. Cells

    We isolate the stem cells from the sample and grow them under documented conditions.

  5. Secretome

    As the cells grow, they release growth factors, exosomes and cytokines into the medium around them. We collect that medium, remove every cell, and test it lot by lot.

  6. Partner brands

    The secretome is supplied to partner brands as an ingredient, and they formulate it into their own products.

The ingredient

What the secretome is.

What cells release, without the cells.

A bottle of gold secretome. Lines point into it from its contents: growth factors, exosomes, cytokines, and no cells.Growth factorsproteins the cells releaseExosomestiny particles the cells releaseCytokinessmall proteins the cells releaseNo cellsevery cell is removed A bottle of gold secretome and its contents: growth factors, exosomes, cytokines, and no cells.Growth factorsproteins the cells releaseExosomestiny particles the cells releaseCytokinessmall proteins the cells releaseNo cellsevery cell is removed

“Secretome” is the scientific word for everything a cell releases. Much of the interest in stem cells has moved from the cells themselves to what they release. We grow menstrual stem cells, then collect what they release in a dedicated step. Cells are left behind and the harvested secretome is tested, sterilized, and ready for formulation.

On an ingredient list it appears as Human Mesenchymal Cell Conditioned Media.

  • Growth factors

    A widely studied family of proteins the cells release as they grow.

  • Exosomes

    Tiny membrane-bound packages of growth factors and proteins.

  • Cytokines

    A family of small proteins the cells release alongside growth factors.

  • No cells

    Cell-free. Contains no live cells.

Quality

Donor

Donor screening

Every donor answers eligibility questions before a kit ships. Depending on how they contribute, screening also includes a health questionnaire, a short call and testing with CLIA-certified labs, and those samples are held until it is complete.

Lab

Traceability

Every sample and every lot carries a code. We can trace a lot back to the day it was collected, and the donor's identity stays separate throughout.

Secretome

Lot testing

Each lot is characterised and tested before it is released, under a documented quality system. We keep the records; brands can ask to see them.

Where it goes

One ingredient, two doors.

Muse Bio secretome as supplied to brands: a bottle of conditioned media and a vial of lyophilised powder

In skincare

Partner brands

Brands formulate the secretome into their own products and stand behind them. One we highlight: Cellora's ONLY1 serum.

Shop Cellora

For brands and formulators

The secretome ingredient

Available as an ingredient for your own formulations, or as a white-labelled growth-factor serum. Our sales team will take it from there.

Talk to sales